genXone SA is a biotech company that offers nucleic acid (DNA and RNA) sequencing services based on the innovative nanopore sequencing technology, Next-Generation Sequencing (NGS), also known as third-generation sequencing.
The company is the first in Poland to be accredited and licensed for commercial use of the nanopore sequencing technology developed by Oxford Nanopore Technologies (ONT). Based on themore than 7-years of experiance with ONT technology, the company creates its own, new solutions in the form of laboratory protocols as well as bioinformatics tools, scripts and algorithms, enabling the use of nanopore sequencing in many areas of science and business, including in genetic diagnostics, food industry, veterinary medicine and agriculture. The experienced team of genXone, which consists of specialists in the field of molecular genetics and bioinformatics, works on modern solutions. The activity of genXone is complemented by the Molecular Diagnostics Laboratory, which conducts research using the Real-Time PCR method, including the detection and quantification of pathogens in various human systems.
Since March 2020 genXone had been highly involved in COVID-19 pandemic fight (molecular testing as well as SARS-CoV-2 genome sequencing).
Our most important projects:
- Nanobiome: the goal of the project is to create a test that evaluates the state of the human microbiome using the Whole Metagenome Sequencing method with nanopore technology. We want to create a tool that supports dieticians and digestive system disorders specialists. Scientifically proven relation between the gut and the brain further proves the important role of microorganisms in proper body functioning. In the future we aim to extend Nanobiome’s range into further areas of our bodies such as skin or mouth. More details can be found here: https://nanobiome.pl/
- Project of sequencing the coronavirus SARS-CoV-2 genome is a natural answer to the pandemic that had dominated the world in the year 2020. Our Research and Development Laboratory, using the newest technology, had already started preparing to sequence the coronavirus SARS-CoV-2 genome back in March.
20.01.2021, we were the first company to successfully detect british variant B.1.1.7 in Poland. We also started a collaboration with WSSE Olsztyn, WSSE Łódź, WSSE Rzeszów. - Project NCBiR, point of which is to develop an innovative test to diagnose postoperative wounds using nanopore sequencing technology, has been on hold since cooperation with the Clinical Hospital in Poznań is impossible due to the pandemic.
Cooperation with Faculty of Biology, Adam Mickiewicz University in Poznan
genXone is going to cooperate with Adam Mickiewicz Univesity in Poznan in development and enrichment of biotechnology major and managing the student education process.. The main principles of cooperation between our company and the university are set out in a letter of intent signed by both parties. This prestigious field of study, which is bioinformatics, is gathering a growing interest of students due to the attractive job prospects in future.
As a part of the cooperation, specialists from genXone will actively participate both in the construction of didactic program in the field of bioinformatics and in the management of the education process. The head of Research and Development at genXone laboratory will join the board in charge of giving opinions and proposing new solutions that extend the range of education. The goal of the cooperation is to create a new education program for bioinformatics that is adjusted to the current potential employer’s requirements. Therefore, the curriculum will tie theoretical classes with the necessary professional practice, which will teach students how to use the acquired knowledge.
Our team:
We work in a dynamic and synchronized team of ambitious experts. We combine knowledge and experience from many fields of business and science. Our shared qualities are flexibility and passion 🙂 In this way we can create unique solutions in response to our Client’s needs.
Our leaders:
Michał Kaszuba (PhD)
President of the The Board, main originator and co-founder of genXone, innovator, entrepreneur.
A graduate of University of Warmia and Mazury (Faculty of Biology) and the Institute of Genetics and Animal Breeding of the Polish Academy of Sciences (PhD in Agricultural Science).
He has gained an extensive experience in research and development projects in the field of biology and genetics.
Awarded multiple times for his accomplishments. Michał Kaszuba is winner of the MMarshal of the Wielkopolska Region award in the Micro Future category (2007), two-time finalist of the well-known Ernst & Young Entrepreneur of the Year competition in the New Business category (2009 and 2010).
Work experience:
2016: Initiator and co-founder of genXone S.A.
2010: President of the Board and co-owner in NewLab System Sp. z o.o.
2010-2014: President of the Board in Inno-Gene SA, a company listed on the Polish stock exchange. In this time period the company realized many development projects and implemented innovative solutions in the field of genetics.
2006-2014: Co-founder and Member of the Board in Centrum Badań DNA sp. z o.o.
Agata Kozioł-Jaworska
Vice-President of operations and Managing director in genXone, expert in business management, specialist in quality management systems. Graduate of Poznan School of Logistics and Poznan University of Technology. She has an extensive experience in scientific projects and successfully introduced two companies to the stock market.
Work experience:
2016 – Board Representative for Quality Management, Administrative Director, and since 2020, Managing director for genXone S.A., since 2022 Vice-President of operations
2012 – Office manager, Member of the Management Board in NewLab System Sp. z o.o.
2011-2014 Head of the Management Board office in Inno-Gene S.A.
2008-2014 Management Board Representative for Quality Management in Centrum Badań DNA sp. z o.o.
Łukasz Krych (PhD)
initiator of basing genXone’s line of business in nanopore technology. He completed his PhD at the University of Copenhagen in Denmark (2011-2014), worked as postdoctoral researcher in ETH Zurich (Switzerland 2016 – 2017), simultaneously has been working as postdoctoral research fellow in University of Copenhagen since 2014. Between 2008 and 2010 he worked as research and development assistant in Centrum Badań DNA in Poznan. He’s the author of 147 international publications in scientific magazines; h-index: 35
- understanding of the effect of diet on microbiological composition in “in vivo” and “in vitro” models of mammalian gastrointestinal tract;
- Development and optimisation of protocols for NGS sequencing (Illumina, MiSeq, NextSeq, Oxford Nanopores) and high-throughput qPCR; research and development of modern molecular tests in diagnostics of genetic diseases and detection of pathogens; analysis of NGS data including sequencing of amplicons, metagenomes and their annotation (Qiime, C ++, R, Matlab, bash); hardware assembly and software management on custom-made computers; construction of Unix-based computing sets, including servers, for advanced data analysis
Łukasz Krych has a strong international academic background as well as a strong experience in a wide range of molecular techniques and NGS data analysis . His main research areas include:
- researching the relationship between gut’s microbiome with human and animal health and sickness.
- molecular genetic and classic microbiological methods to detect, identify and characterize complexes of microorganism groups;
- detection of yeast, bacteria and phages associated with food processing and food pathogens.
- understanding of the effect of diet on microbiological composition in “in vivo” and “in vitro” models of mammalian gastrointestinal tract;
- development and optimization of protocols for NGS sequencing (Illumina, MiSeq, NextSeq and Oxford Nanopores) and high-throughput qPCR.
- research and development of modern molecular tests used in genetic diseases diagnosis and pathogen detection.
- NGS data analysis including sequencing of amplicons, metagenomes and their annotation (Qiime, C ++, R, Matlab, bash).
- hardware assembly and software management on custom-built computers ;
- construction of Unix-based computing sets, including servers, for advanced data analysis